Patients with Hypertension Who Lose Substantial Amounts of Weight Can Positively Impact Risk Factors and Need for Medications
Grant L, Gotthelf L.
Obes 2007;15 suppl:A98.
Objectives: Overweight is a known risk factor for hypertension and weight loss is recommended as the initial therapeutic task. The purpose of this study was to evaluate if hypertensive patients who participate in a structured, research-based behavioral program can positively impact their medical risk factors and need for blood pressure medications.
Subjects: Patients who entered the HMR® Program for Weight ManagementTM with systolic blood pressure > 140 mmHg and diastolic blood pressure > 90 mmHg and were not on blood pressure medications. Data were analyzed for those who completed a follow-up health risk appraisal from January, 2005, to April, 2007, and entered the maintenance program.
Programs: HMR offers a range of weight-loss treatment options, including medically supervised low and very low-calorie diets, moderately restricted diets and phone-based programs as well as long-term maintenance. The program is based on measurable, evidence-based variables allowing for specific goals to be set and compliance to be tracked. All options for weight loss and maintenance focus on the same lifestyle changes: increased physical activity (> 2000 kcal/wk); use of meal replacements (> 35/wk in weight loss and 14/wk in maintenance); increased vegetable and fruit intake (> 35/wk) is included in some weight-loss options and in maintenance.
Results:
|
Measure
|
No BP Medications
at Follow-up
|
On BP Medications
at Follow-up
|
| Number of Patients |
60
|
13
|
| Start Weight |
268 lbs.
|
233 lbs
|
| Weight Loss |
–54 lbs. (20.1%)
|
–4 lbs.
(1.7%)
|
| Total Cholesterol/HDL |
–17.6%
|
–6.5%
|
| Triglycerides |
–30.9%
|
+8.0%
|
| Systolic Blood Pressure |
–24 mmHg
|
–7 mmHg
|
| Diastolic Blood Pressure |
–18 mmHg
|
–14 mmHg
|
| Fasting Blood Glucose |
–5.0%
|
+29.7%
|
Medical changes occurred in addition to substantial decreases and/or elimination of other medications
Conclusions: Patients who lost substantial amounts of weight and made lifestyle changes in a structured weight management program were able to avoid the need for hypertensive medications. Weight loss and lifestyle changes should be the first therapeutic task for hypertensive patients.
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