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Patients at risk for type 2 diabetes substantially improve risk factors in an intensive weight management treatment program.
Weithman C, Gotthelf L, Grant L, O'Brien B.
J Am Diet Assoc 2004;104 suppl 2:A-24.
Summary: Large-scale studies, such as the DPP, have clearly defined the lifestyle changes, including weight management and physical activity, which can impact the progression from pre-diabetes to diabetes. Data were analyzed on 150 patients in the HMR® Program for Weight Management™. Patients lost weight in an intensive behavioral program with a very-low-calorie, or moderately restricted diet (including the maintenance phase of the program). The maintenance program utilizes the same behaviors: record-keeping, weekly attendance, meal replacements, physical activity (minimum of 2,000 calories/week), and vegetables and fruits (minimum of 35 full-cup servings/week). The sample consisted of all maintenance patients who had completed a follow-up health risk appraisal (HRA) during 2002–2003 and had a pre-treatment fasting blood glucose > 100 mg/dl but no diagnosis of diabetes. The average length of time between the initial and follow-up HRA was 3 years. At follow-up, patients were maintaining and average weight loss of 38 lbs or 15% of initial body weight. The average BMI dropped from 39.6 to 33.7 kg/m2. In terms of medical parameters, there were declines in average total cholesterol/HDL ratio (12.4%), triglycerides (14.2%), systolic blood pressure (8 mm/Hg), diastolic blood pressure (8 mm/Hg) and fasting blood glucose (14.3%, a drop from 112–96). Only 3.4% (5 of 150 patients) were taking oral diabetes medications at follow-up. In addition, the number of elevated risk factors dropped from 7 to 3. Overweight patients who are at risk for Type 2 diabetes can make critical lifestyle changes as part of an ongoing intensive treatment program and positively impact their health.
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