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Weight Management Results
One Hundred-pound Weight Losses with an Intensive Behavioral Program: Changes in Risk Factors in 118 Patients with Long-term Follow-up. Am J Clin Nutr 2007;86:301-307
These 118 patients weighed an average of 352 lbs on entering the HMR Program and lost an average of 134 lbs. in 44 weeks. Medication doses were reduced in all patients who entered the program on medications. Medications were discontinued in 66% of all patients, including 100% of patients with dyslipidemia, 67% with hypertension, 73% with diabetes and 83% with degenerative joint disease.
Weight loss and long-term follow-up of severely obese individuals treated with an intense behavioral program. Int J Obes 2007;31:488-493.
Results for 1100 people with BMIs > 40 kg/m2 who completed the 12-week program showed an average weight loss of 77.6 lbs. Twenty-five percent (25%) of this group lost 100 lbs. or more – for an average weight loss of 137.4 lbs. Those who lost > 100 lbs. were maintaining an average of 90.4 lbs. approximately 2 years later while participating in a maintenance program.
Patients with Hypertension Who Lose Substantial Amounts of Weight Can Positively Impact Risk Factors and Need for Medications Obes 2007;15 suppl:A98.
Patients with high blood pressure but not on medications at the time of program entry were followed in maintenance. Patients who lost substantial amounts of weight (average of 54 lbs) and made lifestyle changes (along with decreases in medical risk factors) were able, on average, to avoid the need for hypertensive medications.
High Compliance with Lifestyle Behaviors for Weight Management Is Possible. Obes 2006;14 suppl:A100.
Data from 1305 weight loss and 870 maintenance patients were evaluated for compliance in the HMR® Program for Weight ManagementTM. Having high standards for program compliance and using behavioral strategies to meet these goals leads to high compliance in lifestyle changes (e.g., physical activity) and program variables (e.g., attendance).
Prehypertensive Patients Substantially Improve Risk Factors in a Weight Management Program. Obes 2006;14 suppl:A101.
Initial risk factor data from patients who were prehypertensive when they entered the HMR® Program for Weight ManagementTM were compared with data an average of 2.7 years later. Patients had significant decreases in all measured medical risk factors. 94.3% of patients remained free of blood pressure medications and 84.6% discontinued diabetes medications.
Weight Maintenance with Five Clinic-Based and Phone-Based Treatment Options. Obes 2006;14 suppl:A101.
603 medically supervised patients were maintaining an average of 71.1% of their weight loss (average weight loss was 62.8 lbs.) over a total of 63.9 weeks of treatment. Healthy Solutions patients (n = 259) were maintaining an average of 66% of their weight loss (average weight loss was 41.6 lbs.) over a total of 65.4 weeks of treatment.
Losing Greater Amounts of Weight Leads to Greater Changes in Medical Risk Factors. Obes 2006;14 suppl:A103
Data from 2564 patients in 65 HMR clinics were analyzed by percent of initial body weight kept off. All measured medical risk factors decreased significantly more in those losing the most weight as compared to all other groups. Patients reporting the greatest changes in lifestyle behaviors lost more weight, indicating a dose-response relationship.
Specific and Differential Responses of Serum Lipoproteins to Weight Loss of > 100 Pounds. Obes 2006;14 suppl:A166
Substantial weight loss has selective effects on lipoproteins: LDL cholesterol gradually decreased and then began to increase and triglycerides decreased progressively. HDL cholesterol decreased rapidly in 4—8 weeks, returned to baseline at completion of weight loss and then significantly increased at one year. Overall, weight loss was found to improve all lipoprotein risk factors.
Weight Loss in Five Treatment Options in a Structured Behavioral Program Obes 2006;14 suppl:A101.
The weight loss outcomes of five treatment options in the HMR Program were evaluated. Medically supervised patients (n=734) lost and average of 60.9 lbs. or 22.6% of initial body weight in an average of 29 weeks. Healthy Solutions patients (n=309) lost an average of 41.4 lbs. or 18.5% of initial body weight in an average of 27 weeks.
Long-term follow-up of 1,000 patients shows substantial lifestyle and medical changes. Obes Res 2005;13 suppl:A203.
1,000 maintenance patients were maintaining an average weight loss of 44 pounds (18% of initial body weight) over an average of 2½ years. Participants had made substantial lifestyle changes and had highly significant decreases in all measured medical parameters, such as fasting blood glucose, blood pressure, total cholesterol/HDL ratio, and triglycerides.
A comparison of meal replacements and medication in weight maintenance after weight loss. J Am Coll Nutr 2005;24:347–353.
After an average weight loss of 50.3 lbs. with a very low-calorie diet, using 2 HMR® meal replacement entrees a day was effective in maintaining weight loss within 6 lbs. over one year.
Intensive behavioral program is a successful treatment option for severely obese patients with BMI > 40. Obes Res 2005;13 suppl:A203.
1,136 participants who completed at least 12 weeks in weight loss treatment lost an average of 78.1 lbs. over an average of 37.2 weeks. Nearly ¼ of these participants lost > 100 lbs. and those who entered a maintenance program were keeping off an average of 69% of this weight loss (94.5 lbs.) over an average of 2.7 years.
Response of men and women with BMI > 40 to intensive treatment program for weight management. Obes Res 2005;13 suppl:A144.
This study analyzed data from 1,136 men and women who entered the HMR Program with a BMI > 40 kg/m2 and completed at least 12 weeks of weight loss. Men in this sample tended to sustain more of their weight loss. However, men and women who had lost > 100 lbs. were both maintaining an average weight loss of 27% of initial body weight after 2½ to nearly 3 years while participating in the program.
Weight loss in overweight or obese individuals with different structured interventions in an intense behavioral program. Obes Res 2004;12 suppl:A40.
In a recent sample of weight-loss participants, medically supervised HMR patients lost an average of 56.8 pounds in an average of 24 weeks and HMR Healthy Solutions® patients lost an average of 36.7 pounds in an average of 20 weeks. Average reported physical activity was over 2,000 calories per week for all groups.
Improved long-term maintenance of weight loss with ongoing involvement in weight management program. Obes Res 2004;12 suppl:A41.
Fifty-four participants who lost > 100 lbs. (average weight loss was 140 lbs.) were maintaining 70% of this weight loss (average of 100 lbs.) at an average of over three years.
Reductions in blood pressure and medication costs with 100-pound weight loss. Obes Res 2004;12 suppl:A38.
For participants who lost > 100 lbs., systolic and diastolic blood pressure decreased 12–15%, antihypertensive medications decreased 72%, medication strength decreased 81% and medication cost decreased 78%.
Meal replacement use patterns for patients losing > 100 pounds in a behavioral, low-energy-diet program. Obes Res 2004;12 suppl:A38.
This study reported on the dietary and exercise patterns of 65 patients who had lost > 100 lbs. Most patients consumed only HMR meal replacement shakes initially but slowly increased the intake of HMR Entrees and nutrition bars.
Risk factor reductions with 100-pound weight losses: results for 75 medically treated morbidly obese individuals. Obes Res 2003;11 suppl:A91.
Results from 75 participants who lost > 100 lbs. found that the average weight loss was 136 lbs. or 39% of initial weight over 36 weeks. This weight loss significantly improved all measured CHD risk factors including plasma glucose values, cholesterol, triglycerides, and HDL cholesterol.
Long-term weight-loss maintenance: a meta-analysis of US studies. Am J Clin Nutr 2001;74:579–584.
Individuals who lost greater amounts of weight in shorter amounts of time (e.g., very low-calorie diet) lost significantly more weight overall and kept off more of the weight loss than those following less intensive diets. Additionally, those who exercised more had significantly greater success with weight-loss maintenance than those who exercised less.
Success in behavioral weight management program depends on treatment variables chosen. Obes Res 2001;9 suppl 3:181S.
Behavioral and weight change data from a total of 248 maintenance patients who were active in either 1995 or in 2000 were compared. Due to recent changes in the HMR Program, those who were enrolled in 2000 gained less weight in the maintenance program and participated in more lifestyle behaviors, such as physical activity, meal replacements, and vegetable/fruit intake.
Accountability (attendance and phone calls) is critical for patient success in a weight management program.
Obes Res 2000;8 suppl 1:69S.
Data from 666 maintenance program participants were analyzed to determine the impact of attendance and phone calls on success. Those who attended the program most often and made a greater number of structured phone calls were more successful with weight management and lifestyle behaviors than those who attended less often.
Greater improvement in medical risk factors with greater weight loss/maintenance compared to recommended 5–10%. Obes Res 2000;8 suppl 1:69S.
The average weight loss maintenance for a sample of 1,219 participants from the maintenance program was 43.1 lbs. (17% of initial body weight) over 2 years. Compared to the standard of a 5-10% loss of initial body weight, those maintaining greater amounts of weight demonstrated significant improvements in medical risk factors.
Use of meal replacements associated with greater success in weight maintenance treatment program. J Am Diet Assoc 2000;100 suppl:A-75.
In a sample of 666 participants, those who used > 14 meal replacements per week did better with weight maintenance and participated in more lifestyle behaviors (physical activity, vegetable/fruit intake, attended the program, and kept records) than those who used < 14 meal replacements per week.
Long-term weight maintenance after an intensive weight-loss program. J Am Coll Nutr 1999;18:620–627.
This prospective study documented an average weight loss of 65 lbs. for patients in a medically supervised HMR very low-calorie diet program and reported follow-up data of up to seven years.
Prophylaxis against gallstone formation with ursodeoxyholic acid in patients participating in a very-low-calorie diet program. Ann Intern Med 1995;122:899–905.
Patients from 31 HMR programs participated in a clinical trial that showed ursodeoxycholic acid is highly effective in preventing gallstone formation during a very low-calorie diet.
Food-containing hypocaloric diets are as effective as liquid-supplement diets for obese individuals with NIDDM. Diabetes Care 1994;17:602–604.
Forty individuals with type 2 diabetes, using either all meal replacements or meal replacements plus non-MR foods in an HMR medically supervised program, lost an average of 35 lbs. and improved glycemic, blood lipid, and blood pressure parameters.
Relationship of weight loss to cardiovascular risk factors in morbidly obese individuals. J Am Coll Nutr 1994;14:256–261.
Improvements in cardiovascular risk factors (serum lipids and blood pressure) were significantly and linearly related to the degree of weight loss for 80 morbidly obese patients in a medically supervised HMR program.
Weight loss and 2-year follow-up for 80 morbidly obese patients treated with intensive very-low-calorie diet and an education program. Am J Clin Nutr 1992;56:244–246S.
This follow-up study found that obese individuals in a medically supervised HMR program lost a substantial amount of weight, reduced risk factors, and were maintaining 48% of their weight loss two years after treatment.
Benefits and risks of an intensive very-low-calorie diet program for severe obesity. Am J Gastroenterol 1992;87:6–15.
This article reviewed the use of very low-calorie diets and reported data for three samples of patients enrolled in an HMR program. Patients were maintaining approximately 56% of their initial weight loss two years after treatment.
Comparative weight loss in obese patients restarting a supplemented very-low-calorie diet. Am J Clin Nutr 1992;56:290S–291S.
Patients restarting an HMR very low-calorie diet (VLCD) program were found to have similar rates of weight loss—as well as significant net weight loss—suggesting that repeat VLCDs can be effective.
Safety and effectiveness of a multidisciplinary very-low-calorie diet program for selected obese individuals. J Am Diet Assoc 1991;91:1582–1584.
This study reported the results for the first 100 patients consecutively enrolled in an HMR very low-calorie diet program (up to 42 month follow-up).
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